The effectiveness of Kampo medicines in the treatment of intractable acute, low-tone, sensorineural hearing loss

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  • 急性低音障害型感音難聴難治例に対する漢方薬の効果

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<p>Acute, low-tone, sensorineural hearing loss（ALHL）is generally considered to have a good prognosis; however, it can recur, and some cases progress to Meniere’s disease. Primary treatment of ALHL is important to prevent worsening of hearing loss and onset of Meniere’s disease. We administered Ninjinyoeitou or Goreisan, herbal medications, to patients with intractable ALHL. A 44.4% cure or improvement rate was achieved from among 27 cases administered Ninjinyoeitou. On the other hand, a 20.0% cure or improvement rate was achieved from among 25 cases administered Goreisan. The efficacy of Ninjinyoeitou was significantly better than that of Goreisan. The hearing thresholds at 125Hz and 250Hz in the Ninjinyoeitou group were significantly improved. Ninjinyoeitou has hematopoietic action and is used to treat anemia associated with cancer chemotherapy. We hypothesized that Ninjinyoeitou would improve the impaired blood supply to the stria vascularis and therefore be effective in patients with intractable ALHL.</p>

Journal

  • Otology Japan

    Otology Japan 28 (3), 139-143, 2018

    Japan Otological Society

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