An Endobronchial Aspergilloma with Sarcoidosis

  • Mizushina Yoshiko
    Division of Pulmonary Medicine, Department of Medicine, Jichi Medical University
  • Bando Masashi
    Division of Pulmonary Medicine, Department of Medicine, Jichi Medical University
  • Nakayama Masayuki
    Division of Pulmonary Medicine, Department of Medicine, Jichi Medical University
  • Takasaki Toshikazu
    Division of Pulmonary Medicine, Department of Medicine, Jichi Medical University
  • Mato Naoko
    Division of Pulmonary Medicine, Department of Medicine, Jichi Medical University
  • Kanai Nobuyuki
    Department of Integrative Pathology, Jichi Medical University
  • Fukushima Noriyoshi
    Department of Integrative Pathology, Jichi Medical University
  • Endo Shunsuke
    Division of Thoracic Surgery, Department of Surgery, Jichi Medical University
  • Suzuki Takuji
    Division of Pulmonary Medicine, Department of Medicine, Jichi Medical University
  • Hagiwara Koichi
    Division of Pulmonary Medicine, Department of Medicine, Jichi Medical University

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Other Title
  • サルコイドーシスに合併した気管支内アスペルギローマの1例

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<p>Background. Pulmonary sarcoidosis is often accompanied by infections with the Aspergillus species, but endobronchial aspergilloma is uncommon. Case. A 69-year-old man was admitted to Jichi Medical University Hospital for detailed examination of abnormal chest radiography. Chest computed tomography (CT) showed a single nodular shadow in a bronchiectatic lesion in the lingula. Bronchoscopic biopsy revealed the presence of mycelia of Aspergillus species. Thoracoscopic lingulectomy was performed. Histological examination revealed aspergilloma in the bronchiectatic lesions together with non-caseating epithelioid granulomas suggestive of sarcoidosis. The patient was observed medication-free thereafter, and no recurrences of Aspergillus infection were detected in 4 years. Conclusion. A case of endobronchial aspergilloma with sarcoidosis is reported. Aspergilloma was observed as a single nodule in a bronchiectatic lesion in the chest CT. Surgical resection was curative and the disease has not recurred.</p>

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