Anaphylaxis due to Fish and a Beauty Nutrition Drink, with Fish Collagen as the Causative Allergenic Component

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  • ADACHI Atsuko
    Department of Dermatology, Hyogo Prefectural Kakogawa Medical Center
  • OTSUKA Haruhiko
    Department of Dermatology, Hyogo Prefectural Kakogawa Medical Center
  • YAMANO Nozomi
    Department of Dermatology, Hyogo Prefectural Kakogawa Medical Center
  • HAMAOKA Dai
    Department of Dermatology, Hyogo Prefectural Kakogawa Medical Center
  • INOUE Yusuke
    Department of Dermatology, Hyogo Prefectural Kakogawa Medical Center
  • KOBAYASHI Yukihiro
    Department of Food Science and Technology, Tokyo University of Marine Science and Technology

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Other Title
  • 魚コラーゲンが原因抗原と考えられた魚および美容ドリンク剤によるアナフィラキシーの１例
  • 症例 魚コラーゲンが原因抗原と考えられた魚および美容ドリンク剤によるアナフィラキシーの1例
  • ショウレイ サカナ コラーゲン ガ ゲンイン コウゲン ト カンガエラレタ サカナ オヨビ ビヨウ ドリンクザイ ニ ヨル アナフィラキシー ノ 1レイ

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<p>　The patient was a 22-year-old woman who exhibited oral allergy syndrome and/or food-dependent exercise-induced anaphylaxis upon ingestion of several types of fish and a beauty drink containing fish collagen peptide. She tested positive for the specific IgE (CAP FEIA) of many types of fish. On the prick test, she was strongly positive for all fish, fish products, and a beauty drink containing fish collagen and fish collagen peptide, the main component. Using an ELISA method, we diagnosed the allergen component of our patient as fish collagen and not parvalbumin, which is the major allergen from fish. The collagen peptide has a domestic animal origin and fish origin, and as an industrial raw material, is used as a powder and water solution. As the collagen peptide is included extensively in food and health drinks as well as in cosmetics, caution is necessary for patients with fish allergy.</p>

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