Study on Long-term Effect of Specific Health Guidance on Lab Test Values Using Propensity Score

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  • 傾向スコアを用いた特定保健指導の長期的な検査値改善効果の検証
  • ケイコウ スコア オ モチイタ トクテイ ホケン シドウ ノ チョウキテキ ナ ケンサチ カイゼン コウカ ノ ケンショウ

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<p>Objective: To evaluate the long-term effectiveness of Specific Health Guidance, we investigated its improving effect on lab test values up to 6 years later.</p><p>Methods: In the period 2008 – 2010, 2,152 people receiving active support were designated as an intervention group, and 6,523 people not receiving active support as a control group. Covariate adjustment by propensity score matching was carried out, matching 1 person in the intervention group with 2 in the control group, and the improving effect on lab test values for persons receiving active support was examined. The effect of weight change after 1 year was verified, stratifying the intervention group into to 6 subgroups by weight change: 1% or more increase, ± 1% or less, 1 – 2% decrease, 3 – 4% decrease, 5 – 6% decrease, 7% or greater decrease.</p><p>Results: Significant improvements in body weight, abdominal circumference, blood pressure, FPG, HbA1c and triglyceride were maintained over 6 years. Also, a significant improvement in HDL-C was maintained over 5 years, in ALT over 4 years, in γ-GTP over 3 years, in AST over 2 years and in LDL-C after 1 year. Regarding weight loss after 1 year, in a subgroup with a 3 – 4% decrease in weight, a significant improvement in lab test values was achieved and continued until 1-2 years later. A subgroup with a 5 – 6% decrease achieved a significant improvement in lab test values lasting 3 – 4 years and one with a 7% or greater decrease a significant improvement lasting 5 – 6 years.</p><p>Conclusion:The duration of the improving effect differed depending on the lab test parameter and it was found that with a greater weight loss, the duration of the improving effect was longer.</p>

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