Cytologic features of a clear cell variant of a solid pseudopapillary neoplasm of the pancreas in an adult male patient

DOI Web Site 9 References
  • NAGATA Ikuko
    Section of Pathological Research and Laboratory, JA Hiroshima General Hospital
  • TAKATA Ai
    Section of Pathological Research and Laboratory, JA Hiroshima General Hospital
  • OKAMOTO Atsuko
    Section of Pathological Research and Laboratory, JA Hiroshima General Hospital
  • IMACHI Kaita
    Section of Pathological Research and Laboratory, JA Hiroshima General Hospital
  • DAIMARU Yutaka
    Section of Pathological Research and Laboratory, JA Hiroshima General Hospital Department of Pathology, JA Hiroshima General Hospital

Bibliographic Information

Other Title
  • 膵 clear cell variant of solid pseudopapillary neoplasm の 1 例
  • —A case report—

Search this article

Description

<p>Background : We report herein on the cytomorphological features of a clear cell variant of a solid pseudopapillary neoplasm in endoscopic ultrasound-guided fine-needle aspiration cytology (EUS-FNAC) and tumor imprint cytology.</p><p>Case : A 38-years-old Japanese man presented with abdominal pain. He had a pancreatic tumor measuring about 13 mm. EUS-FNAC and minimized resection were performed. In both the EUS-FNAC and imprint cytology findings, tumor cells were observed with vacuolation, rounded and eccentric nuclei, nuclear grooves and fine evenly distributed chromatin. On the histological findings, the tumor was mostly composed of vacuolated clear cells with solid growth. Immunohistochemistry revealed positive staining for vimentin, CD-10 (membrane staining) and β-catenin (cytoplasm and nuclei staining) of the neoplastic cells. Based on the above panel the tumor was diagnosed as a clear cell variant of a solid pseudopapillary neoplasm (CCV-SPN).</p><p>Conclusion : We present a case of a rare tumor diagnosed as a CCV-SPN arising in the pancreatic head and body in a young man. The appearance of tumor cells with large, clear cytoplasmic vacuolation in EUS-FNAC and imprint cytology findings is useful for the accurate diagnosis of a CCV-SPN. Immunohistochemistry is necessary for diagnosing and distinguishing CCV-SPNs from other malignancies.</p>

Journal

References(9)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top