Validation of the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) Score for the Head and Neck Region

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  • Ishikawa Chie
    Department of Otorhinolaryngology, Head and Neck Surgery, Graduate School of Biomedical Sciences, Hiroshima University
  • Hamamoto Takao
    Department of Otorhinolaryngology, Head and Neck Surgery, Graduate School of Biomedical Sciences, Hiroshima University
  • Ishino Takashi
    Department of Otorhinolaryngology, Head and Neck Surgery, Graduate School of Biomedical Sciences, Hiroshima University
  • Ueda Tsutomu
    Department of Otorhinolaryngology, Head and Neck Surgery, Graduate School of Biomedical Sciences, Hiroshima University
  • Takeno Sachio
    Department of Otorhinolaryngology, Head and Neck Surgery, Graduate School of Biomedical Sciences, Hiroshima University

Bibliographic Information

Other Title
  • 耳鼻咽喉科領域における壊死性筋膜炎について LRINEC スコアを用いた検討
  • ジビ インコウカ リョウイキ ニ オケル エシセイキンマクエン ニ ツイテ LRINEC スコア オ モチイタ ケントウ

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Description

<p>　Necrotizing fasciitis (NF) is an aggressive soft tissue infection that results in the necrosis of muscle and fascia. It is a serious disease of sudden onset that progresses rapidly. Early diagnosis is difficult as the disease often initially looks like a simple superficial skin infection or cellulitis. LRINEC score (Laboratory Risk Indicator for Necrotizing Fasciitis score) has been introduced as an auxiliary diagnostic tool for NF in the early phase. As there are few reports regarding the availability of the LRINEC score for NF in the head and neck region, we conducted this study to compare the LRINEC score for NF and cellulitis. The NF group consisted of 12 cases encountered by us and 8 cases reported by the Japan medical abstract society. The cellulitis group consisted of 13 cases encountered by us. The average LRINEC score was 7.2 in the NF group and 1.6 in the cellulitis group, with a statistically significant difference in the score between the two groups. The serum CRP and WBC count were also significantly different between the two groups. A score of 6 was found to be a reasonable cutoff value for the diagnosis of NF with a sensitivity of 85%, specificity of 92%, positive predictive value of 94%, and negative predictive value of 80%. We concluded that the LRINEC score is an easily available auxiliary diagnostic tool also for NF in the head and neck region.</p>

Journal

  • Nippon Jibiinkoka Gakkai Kaiho

    Nippon Jibiinkoka Gakkai Kaiho 122 (6), 884-890, 2019-06-20

    Japanese Society of Otorhinolaryngology-Head and neck surgery

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