A new approach at the early stage of small molecule drug discovery Open innovation by leveraging compound library

DOI
  • Kamiyama Tsutomu
    Mitsubishi Tanabe Pharma Corporation, Soyaku, Innovative Research Division, Discovery Technology Laboratories

Bibliographic Information

Other Title
  • 前期低分子創薬での新たな試み─化合物ライブラリを活用したオープンイノベーション─

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Description

<p>For pharmaceutical companies focusing on to deliver new chemical entities, the circumstance around the pharmaceutical industries becomes more severe in these years. From the point of view of reducing cost and improving speed, many companies try to introduce open innovation as a crucial idea for departing from “go it alone”. Using this opportunity, I introduce how we apply open innovation at the stage of lead generation as a key item of compound library for HTS. For improving diversity of chemical library, we have joined Japanese Compound Library Consortium (J-CLIC) for group purchasing compounds and shared compound libraries with Astellas. For adding value and making full use of potential of our library, we have joined Drug Discovery Innovation and Screening Consortium (DISC) supported by Japan Agency for Medical Research and Development (AMED). And we have initiated screening activities against anti-malaria supported by the Global Health Innovative Technology Fund (GHIT Fund).</p>

Journal

  • MEDCHEM NEWS

    MEDCHEM NEWS 27 (1), 14-18, 2017-02-01

    The Pharmaceutical Society of Japan

Keywords

Details 詳細情報について

  • CRID
    1390845713081551872
  • NII Article ID
    130007670689
  • DOI
    10.14894/medchem.27.1_14
  • ISSN
    24328626
    24328618
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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