Comparison of Clinical Characteristics of Human Metapneumovirus and Respiratory Syncytial Virus Infections in Hospitalized Young Children
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- Taniguchi Akinobu
- Department of Pediatrics, Nagoya University Graduate School of Medicine Department of Neonatology, Ogaki Municipal Hospital
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- Kawada Jun-ichi
- Department of Pediatrics, Nagoya University Graduate School of Medicine
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- Go Kiyotaka
- Department of Pediatrics, Nagoya University Graduate School of Medicine
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- Fujishiro Naozumi
- Department of Pediatrics, Nagoya University Graduate School of Medicine
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- Hosokawa Yosuke
- Department of Pediatrics, Nagoya University Graduate School of Medicine
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- Maki Yuki
- Department of Pediatrics, Nagoya University Graduate School of Medicine
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- Sugiyama Yuichiro
- Department of Pediatrics, Nagoya University Graduate School of Medicine
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- Suzuki Michio
- Department of Pediatrics, Nagoya Memorial Hospital
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- Tsuji Takeshi
- Department of Pediatrics, Okazaki City Hospital
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- Hoshino Shin
- Department of Pediatrics, Kasugai City Hospital
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- Muramatsu Hideki
- Department of Pediatrics, Nagoya University Graduate School of Medicine
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- Kidokoro Hiroyuki
- Department of Pediatrics, Nagoya University Graduate School of Medicine
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- Kinoshita Fumie
- Center for Advanced Medicine and Clinical Research, Nagoya University Hospital
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- Hirakawa Akihiro
- Center for Advanced Medicine and Clinical Research, Nagoya University Hospital Department of Biostatistics and Bioinformatics, Graduate School of Medicine, The University of Tokyo
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- Takahashi Yoshiyuki
- Department of Pediatrics, Nagoya University Graduate School of Medicine
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- Sato Yoshiaki
- Department of Pediatrics, Nagoya University Graduate School of Medicine Division of Neonatology, Center for Maternal-Neonatal Care, Nagoya University Hospital
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- Natsume Jun
- Department of Pediatrics, Nagoya University Graduate School of Medicine Department of Developmental Disability Medicine, Nagoya University Graduate School of Medicine
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説明
<p>Human metapneumovirus (HMPV) and respiratory syncytial virus (RSV) are the leading causes of acute respiratory tract infection in children, and clinical manifestations of these virus infections are considered similar. To investigate the differences in clinical characteristics between HMPV and RSV infections in young children, we prospectively enrolled children < 3 years old who required hospitalization with acute respiratory tract infection due to HMPV or RSV at 10 hospitals in Japan. We enrolled 48 children with HMPV infection and 141 with RSV infection. Patients with HMPV infection were older than those with RSV infection. High-grade fever was more frequently observed in patients with HMPV infection, whereas no significant differences in respiratory symptoms were apparent. Abnormal serum lactate dehydrogenase values and consolidation shadows on chest X-ray were more frequently observed in patients with HMPV infection. During hospitalization, nasal mucus suction was more frequently required in patients with RSV infection. On the other hand, β2-adrenergic agonists, corticosteroids, and leukotriene receptor antagonists were more frequently used in patients with HMPV infection. These findings suggest that HMPV and RSV infections show similar respiratory symptoms, but HMPV infection is more likely to lead to the development of pneumonia, at least among hospitalized young children.</p>
収録刊行物
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- Japanese Journal of Infectious Diseases
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Japanese Journal of Infectious Diseases 72 (4), 237-242, 2019
国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会
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詳細情報 詳細情報について
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- CRID
- 1390845713084233344
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- NII論文ID
- 130007682337
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- NII書誌ID
- AA1132885X
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- ISSN
- 18842836
- 13446304
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- NDL書誌ID
- 029846095
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- PubMed
- 30814460
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
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