Probiotics/prebiotics have the potential to prevent the onset of allergy
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- Ito Komei
- Department of General Pediatrics, Aichi Children's Health and Medical Center
Bibliographic Information
- Other Title
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- プロ・プレバイオティクスによるアレルギー予防は可能か
- Pro:アレルギー予防は可能である
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Abstract
<p>Many immunological studies have revealed a critical role of the gut microflora in the maintenance of systematic immunity. Probiotics are defined as "live microorganisms that, when administered in adequate amounts, confer a health benefit on the host". Most corresponding microorganisms are of the Bifidobacterium and Lactobacillus species. Probiotic bacteria may have a direct ability to alter the human immune system, because not only live bacteria, but also dead bacteria, can effectively promote the acquisition of oral tolerance.</p><p>Recent studies have focused on the effects of short chain fatty acids produced by the gut microflora on the development of regulatory T cells and oral tolerance. The dominant microbiota is classified into Clostridium species, which might have different activity from classical probiotic bacteria.</p><p>Prebiotics is defined as "a substrate that is selectively utilized by host microorganisms conferring a health benefit". Typical materials include dietary fiber and non-digestible oligosaccharides. Some prebiotics increase the amount of short chain fatty acid in the gut, and are expected to be effective for preventing allergic diseases.</p>
Journal
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- Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology
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Nihon Shoni Arerugi Gakkaishi. The Japanese Journal of Pediatric Allergy and Clinical Immunology 34 (1), 147-152, 2020-03-20
THE JAPANESE SOCIETY OF PEDIATRIC ALLERGY AND CLINICAL IMMUNOLOGY
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Details 詳細情報について
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- CRID
- 1390846609816466432
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- NII Article ID
- 130007815634
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- ISSN
- 18822738
- 09142649
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed