A case of calcium channel blockers and angiotensin receptor blockers poisoning.

  • Namikata Yu
    Department of Emergency and Critical Care Medicine, Yokohama Rosai Hospital
  • Oya Seiro
    Department of Emergency and Critical Care Medicine, Yokohama Rosai Hospital
  • Morino Kyoko
    Department of Emergency and Critical Care Medicine, Yokohama Rosai Hospital
  • Takeshita Ryo
    Department of Emergency and Critical Care Medicine, Yokohama Rosai Hospital
  • Mizuno Ren
    Department of Emergency and Critical Care Medicine, Yokohama Rosai Hospital
  • Uechi Takahiro
    Department of Emergency and Critical Care Medicine, Yokohama Rosai Hospital
  • Irihukuhama Yuna
    Department of Emergency and Critical Care Medicine, Yokohama Rosai Hospital
  • Kashiwa Kenichiro
    Department of Emergency and Critical Care Medicine, Yokohama Rosai Hospital
  • Mita Naoto
    Department of Emergency and Critical Care Medicine, Yokohama Rosai Hospital
  • Nakamori Tomoki
    Department of Emergency and Critical Care Medicine, Yokohama Rosai Hospital
  • Kinoshita Hirohisa
    Department of Emergency and Critical Care Medicine, Yokohama Rosai Hospital

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Other Title
  • カルシウム拮抗薬, アンジオテンシン II 受容体拮抗薬中毒の1例

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<p>This is a report on the case of a patient who went into a state of shock due to an overdose on calcium channel blockers, angiotensin receptor blockers and benzodiazepines. The 61-year-old female was brought to the emergency department in a state of shock. A careful review of her medical history revealed that she had calcium channel blocker poisoning. Fluid resuscitation was started, but the state of shock did not improve. After administrating noradrenaline, glucagon and calcium gluconate, she became hemodynamical stable. Calcium channel blocker poisoning causes lethal bradycardia and hypotension. It is important to know the mechanism of the drug kinetics and the specific treatments for each drug.</p>

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