Performance evaluation of VITROS XT7600 in plasma D-dimer level determination in case of disaster

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  • 災害時の運用を想定したVITROS XT7600によるDダイマー測定の検討

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Abstract

<p>Several studies have reported an increased risk of venous thromboembolism (VTE) after a disaster such as an earthquake. We should determine blood D-dimer levels and/or perform an ultrasound testing to screen for VTE. However, automated and high-throughput screening tests would be required when an earthquake would occur and lifelines are stopped. In this study, we evaluated the performance of the waterless autoanalyzer VITROS XT7600 in plasma D-dimer level determination. We used the Nanopia D-dimer as the reagent for VITROS XT7600 and the LiasAuto D-dimer for CS-5100 for comparison. Intra-assay precision showed CVs of 5.0% (low level) and 1.6% (high level). The correlation was excellent (y = 0.7188x + 0.8013, r = 0.9253). VITROS XT7600 required 1 hour and 15 minutes to finish measuring 50 samples. These results suggest that VTE screening using the D-dimer for VITROS XT7600 is useful with high throughput and reliability.</p>

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