Kerartoconus detection index derived from a placido ring topographer

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  • Itoi Motohiro
    Department of Ophthalmology, Kyoto Prefectural University of Medicine
  • Hieda Osamu
    Department of Ophthalmology, Kyoto Prefectural University of Medicine
  • Teramukai Satoshi
    Department of Biostatistics, Kyoto Prefectural University of Medicine
  • Kinoshita Shigeru
    Department of Ophthalmology, Baptist Eye Institute Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine
  • Sotozono Chie
    Department of Ophthalmology, Kyoto Prefectural University of Medicine

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Other Title
  • Placido型角膜形状解析装置から得られる円錐角膜診断指標の比較

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Abstract

<p>Purpose: To evaluate the diagnostic ability of the keratoconus index compared with other keratoconus (KC) screening indices.</p><p>Method: We enrolled patients who underwent examination via Pentacam HR®, PR-7000® and TMS-4®, and classified into either the normal or KC group based on D-index. The keratoconus index measured by PR-7000®, and KCI (Keratoconus Index) and KSI (Keratoconus Suspective Index) measured by TMS-4® were evaluated. The area under the receiver-operating-characteristics (AU-ROC) and confidence interval (CI) was calculated to assess the diagnostic ability of the indices.</p><p>Results: This study involved 40 eyes of 40 KC patients and 80 eyes of 80 normal subjects. No significant difference was found in AU-ROC between the keratoconus index, KCI, and KSI (0.950 CI: 0.901–1.000, 0.963 CI: 0.921–1.000, and 0.963 CI: 0.916–1.000, respectively).</p><p>Conclusions: The keratoconus index, showed large AUROC as well as KCI and KSI, which may be an effective diagnostic option for detecting KC.</p>

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