Optimization of reactive oxygen species production in anti-infection system utilizing sonocatalysis
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- Tominaga Mayu
- Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan
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- Kaya Akio
- Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan
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- Nitta Naotaka
- Health Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan
Bibliographic Information
- Other Title
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- 超音波触媒活性を用いた感染防止システムにおける活性酸素種生成の最適化に関する検討
Abstract
<p>In order to solve the problem of infection at the exit of the catheter, a anti-infective system that the irradiates ultrasound to titanium dioxide (TiO2) particles bonded on the cuff and produces the reactive oxygen species (ROS), has been studied (Tominaga et al., 2019). In this study, conditions for maximizing ROS production while ensuring safety during percutaneous ultrasonic irradiation were investigated. By using a planar transducer (500 kHz, 45 mm), continuous wave of ultrasound was irradiated to a suspension consisting of diluted methylene blue (MB) solution and TiO2 particles. The ROS production was evaluated by the absorbance of the MB solution and the safety was evaluated by the temperature rise on the transducer surface. As the result, as the above conditions, the ultrasound intensity of 1 W, the TiO2 particles of 10 mg, and the total irradiation time of 15 minutes were determined.</p>
Journal
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- Transactions of Japanese Society for Medical and Biological Engineering
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Transactions of Japanese Society for Medical and Biological Engineering Annual58 (Abstract), 254-254, 2020
Japanese Society for Medical and Biological Engineering
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Details 詳細情報について
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- CRID
- 1390848250134306048
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- NII Article ID
- 130007884910
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- ISSN
- 18814379
- 1347443X
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed