Organ toxicity evaluation using Microphysiological Systems (MPS)

DOI
  • ISHIDA Seiichi
    Division of Pharmacology, National Institute of Health Sciences

Bibliographic Information

Other Title
  • 生体模倣システム（MPS）を用いた臓器毒性評価

Description

<p>In recent years, attempts to predict organ toxicity in vitro by using MPS (Microphysiological Systems) that mimics and reproduces the tissue structure in a living body have been widespread. In the background of these technologies, advances in engineering research such as cell culture, surface processing, and micro-engineering play an important role. On the other hand, there is an approach to extrapolate such in vitro results to clinical practice using PBPK and QSP/QST. This symposium considers future prospects for reducing the side effects of pharmaceuticals by fusing the two technologies.</p>

Journal

Details 詳細情報について

  • CRID
    1390848647545259008
  • NII Article ID
    130007898637
  • DOI
    10.14869/toxpt.47.1.0_s28-1
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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