Enterovirus 71 from Fatal and Nonfatal Cases of Hand, Foot and Mouth Disease Epidemics in Malaysia, Japan and Taiwan in 1997-1998
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- Shimizu Hiroyuki
- Department of Virology II, National Institute of Infectious Diseases, Japan
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- Utama Andi
- Department of Virology II, National Institute of Infectious Diseases, Japan
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- Yoshii Kumiko
- Department of Virology II, National Institute of Infectious Diseases, Japan
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- Yoshida Hiromu
- Department of Virology II, National Institute of Infectious Diseases, Japan
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- Yoneyama Tetsuo
- Department of Virology II, National Institute of Infectious Diseases, Japan
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- Sinniah Mangalam
- Division of Virology, Institute for Medical Research, Malaysia
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- Yusof Mohd Apandi Bin
- Division of Virology, Institute for Medical Research, Malaysia
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- Okuno Yoshinobu
- Laboratory of Virology, Osaka Prefectural Institute of Public Health, Japan
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- Okabe Nobuhiko
- Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Japan
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- Shih Shin-Ru
- School of Medical Technology, and Graduate Institute of Clinical Medicine, Chang Gung University College of Medicine and Memorial Hospital, Taiwan
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- Chen Hour-Young
- Department of Virology, National Institute of Preventive Medicine, Department of Health, Taiwan
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- Wang Gong-Ren
- Department of Virology, National Institute of Preventive Medicine, Department of Health, Taiwan
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- Kao Chuan-Liang
- School of Medical Technology, National Taiwan University College of Medicine, Taiwan
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- Sheuh-Shen Chang Kenneth
- School of Medical Technology, and Graduate Institute of Clinical Medicine, Chang Gung University College of Medicine and Memorial Hospital, Taiwan
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- Miyamura Tatsuo
- Department of Virology II, National Institute of Infectious Diseases, Japan
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- Hagiwara Akio
- Department of Virology II, National Institute of Infectious Diseases, Japan
この論文をさがす
説明
<p>Enterovirus 71 (EV71), one of the major causative agents for hand, foot and mouth disease (HFMD), is sometimes associated with severe central nervous system diseases. In 1997, in Malaysia and Japan, and in 1998 in Taiwan, there were HFMD epidemics involving sudden deaths among young children, and EV71 was isolated from the HFMD patients, including the fatal cases. The nucleotide sequences of each EV71 isolate were determined and compared by phylogenetical analysis. EV71 strains from previously reported epidemics belonged to genotype A-1, while those from recent epidemics could be divided into two genotypes, A-2 and B. In Malaysia, genotype A-2 was more prevalent, while in Japan and Taiwan, B genotype was more prevalent. Two isolates from fatal cases in Malaysia and one isolate from a fatal case in Japan were genotype A-2. However, all isolates from three fatal cases in Taiwan belonged to genotype B. The severity of the HFMD did not link directly to certain genotypes of EV71.<tt> </tt></p>
収録刊行物
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- Japanese Journal of Infectious Diseases
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Japanese Journal of Infectious Diseases 52 (1), 12-15, 1999-03-31
国立感染症研究所
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詳細情報 詳細情報について
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- CRID
- 1390849376465081088
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- NII論文ID
- 130007934504
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- NII書誌ID
- AA1132885X
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- ISSN
- 18842836
- 13446304
- http://id.crossref.org/issn/13446304
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- NDL書誌ID
- 4845511
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- PubMed
- 10808253
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- 本文言語コード
- en
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- JaLC
- NDLサーチ
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