安静時における一過性の高濃度酸素吸入が心拍変動及び酸化ストレスに与える影響

DOI Web Site

書誌事項

タイトル別名
  • Effect of acute hyperoxic inhalation on heart rate variability and oxidative stress
  • アンセイジ ニ オケル イッカセイ ノ コウノウド サンソ キュウニュウ ガ シンパク ヘンドウ オヨビ サンカ ストレス ニ アタエル エイキョウ

この論文をさがす

抄録

<p>Hyperoxic inhalation, or oxygen inhalation by a high-concentration oxygen generator at rest, is used as a method for recovery from fatigue for athletes. However, it is feared that the increase in reactive oxygen species generation related to hyperoxic inhalation may cause some disadvantages as well. The purpose of this study was to investigate whether hyperoxic inhalation affects pulse rate, oxygen dynamics in the blood, autonomic nerve activity and oxidative stress. Ten healthy male subjects participated in two experimental sessions on two different days. Subjects inhaled hyperoxic air (40% O2) or control air (20.9% O2) for 60 minutes in a sitting position, then rested for 5 minutes. We measured arterial oxygen saturation (SpO2), pulse rate, autonomic nerve activity, oxygenation hemoglobin (oxy-Hb), deoxygenation hemoglobin (deoxy-Hb) during each inhalation, general physical condition (visual analog scale), reactive oxygen metabolites (d-ROMs) and biological antioxidant potential (BAP) before and immediately after each inhalation. There was no significant difference in d-ROMs and BAP between the two groups. HF normalized unit (HFnu, HFnu=HF/(LF+HF)×100) was used as an index of parasympathetic activity in autonomic nervous activity. HF normalized unit was significantly higher with the hyperoxic air than the control air (p<0.05), and in the rate of increase after the rest, significant difference was observed between the conditions 25 minutes after the inhalation. These results suggest that 60 minutes of hyperoxic inhalation does not cause oxidative stress, nor effect the balance of parasympathetic activity of the autonomic nervous activity, and is considered as effective for maintaining the parasympathetic activity as compared with the inhalation of the control air.</p>

収録刊行物

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ