A Case of Maxillary Sinus Small Cell Carcinoma with Cancer-associated Retinopathy

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  • Shimamura Ayumi
    Department of Otolaryngology, Head and Neck Surgery, University of Yamanashi
  • Matsuoka Tomokazu
    Department of Otolaryngology, Head and Neck Surgery, University of Yamanashi
  • Hatsushika Kyousuke
    Department of Otolaryngology, Head and Neck Surgery, University of Yamanashi
  • Yonaga Takaaki
    Department of Otolaryngology, Head and Neck Surgery, University of Yamanashi
  • Sakurai Daiju
    Department of Otolaryngology, Head and Neck Surgery, University of Yamanashi
  • Masuyama Keisuke
    Department of Otolaryngology, Head and Neck Surgery, University of Yamanashi Suwa Central Hospital

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Other Title
  • 癌関連網膜症を発症し早期に診断に至った上顎洞小細胞癌例

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Abstract

<p>A 60-year-old male visited our hospital with complaints of rapid reduction in visual acuity and narrowing of the visual field. Upon MRI examination, a left maxillary sinus tumor was found. A biopsy was performed and the patient was diagnosed with small cell carcinoma. Anti-recoverin autoantibodies were also detected; thus, the ocular symptoms were thought to be due to cancer-associated retinopathy (CAR). The patient was treated with chemoradiotherapy and oral corticosteroids; however, while the tumor disappeared, his visual disorder remained. CAR is a rare, tumor-related syndrome and standard treatment has yet to be established. To our knowledge, this is the first case report of CAR associated with small cell carcinoma of the paranasal sinuses. When sudden visual impairment is seen in a patient with suspected malignancy, co-existence of CAR should be considered.</p>

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