iNPHは本当にtreatable dementiaなのだろうか？

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  • 石川 正恒
    洛和ヴィライリオス 音羽病院正常圧水頭症センタ−
  • 山田 茂樹
    音羽病院正常圧水頭症センタ− 滋賀医科大学 脳神経外科
  • 宮嶋 雅一
    順天堂東京江東高齢者医療センター 脳神経外科
  • 數井 裕光
    高知大学医学部神経精神科講座
  • 森 悦朗
    大阪大学大学院 行動神経学・神経精神医学寄附講座

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Abstract

<p>Idiopathic normal pressure hydrocephalus (iNPH) is known as a “treatable dementia”. In contrast to evident improvement of gait disturbance after surgery, improvement of dementia appears to be equivocal. Herein, we investigate shunt effectiveness on long-term care (LTC). Among 83 patients in SIN2(Study of idiopathic normal pressure hydrocephalus-2), 69 patients, whose LTC data were recorded, were subjected in this study. Data were analysed using generalized linear mixed model.</p><p>Disability in LTC significantly improved 12 months after surgery. Dementia in LTC was improved, but were not statistically significant. Random effects did not affect estimates of outcomes. Further investigations for improvement of dementia in iNPH are necessary.</p>

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