HA複合型TCP骨補填材の合成とHHP時のCa/P比変更による化学反応制御の試み

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  • Synthesis of HA/TCP bone filling material and attempt of chemical reaction control by changing Ca/P ratio in HHP process

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<p>Currently, the population is ageing in Japan. Bone diseases are increasing with the ageing of the population. Porous bone filling material containing β-TCP has been widely used in clinical applications for this treatment. β-TCP porous material has high bioabsorbability. However, there are problems that β-TCP porous material has low compressive strength and cannot keep strength up to bone replacement. Therefore, we are tried to synthesize bone filling materials using the HHP method. By using the HHP method, it is expected that both strength and porosity can be achieved. We use this method to composite HA to β-TCP. As a result, we succeeded in synthesizing HA composite β-TCP bone filling material. However, the HA content was nearly 42%. The bioabsorbability is expected to decrease as the HA content increases. Therefore, it is necessary to suppress the HA content, so we tried to control the chemical reaction during HHP. The Ca/P ratio was changed for this purpose, and the mechanical properties were also investigated. As the result, the HA content was suppressed to less than 10%, and the β-TCP content was up to 80%. So, it was possible to synthesize bone filling material with a high bioabsorbability. The strength and porosity were respectively 59.0 MPa and 48.4%, and synthesized material had high strength than previous material.</p>

収録刊行物

  • 年次大会

    年次大会 2020 (0), J02125-, 2020

    一般社団法人 日本機械学会

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