Lipid droplets are formed in 2-cell-like cells
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- FURUTA Asuka
- Laboratory for Epigenetic Regulation, Department of Bio-Science, Nagahama Institute of Bio-Science and Technology, Shiga 526-0829, Japan
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- NAKAMURA Toshinobu
- Laboratory for Epigenetic Regulation, Department of Bio-Science, Nagahama Institute of Bio-Science and Technology, Shiga 526-0829, Japan
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Description
<p> Embryonic stem (ES) cells, derived from the inner cell mass of a blastocyst, are believed to pluripotent cells and give rise to embryonic, but not extraembryonic, tissues. In mice, totipotent 2-cell stage embryo-like (2-cell-like) cells, which are identified by reactivation of murine endogenous retrovirus with leucin transfer RNA primer (MuERV-L), arise at a very few frequencies in ES cell cultures. Here, we found that a lipid droplet forms during the transition from ES cells to 2-cell-like cells, and we propose that 2-cell-like cells utilize a unique energy storage and production pathway.</p>
Journal
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- Journal of Reproduction and Development
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Journal of Reproduction and Development 67 (2), 79-81, 2021
The Society for Reproduction and Development
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Details 詳細情報について
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- CRID
- 1390850711114293248
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- NII Article ID
- 130008028380
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- NII Book ID
- AA10936678
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- ISSN
- 13484400
- 09168818
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- NDL BIB ID
- 031407328
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- PubMed
- 33563871
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed