Spinal Axonopathy in a Holstein-Friesian Heifer

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  • ホルスタイン種育成牛における脊髄軸索変性症の1例
  • ホルスタインシュ イクセイギュウ ニ オケル セキズイジクサクヘンセイショウ ノ 1レイ

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Abstract

<p>A pastured Holstein-Friesian heifer of 9 month-old was hospitalized with the chief complaint of staggering hind limbs. Medication was ineffective and the cow experienced astasia. On physical examination, knuckle-like forelegs, weakness of hind limbs, and loss of the tail force were observed. Knee reflex and flexion reflex of hind limbs decreased, and crossed extension reflex was enhanced on neurological examination. Necropsy showed no significant lesions. Histopathological examination revealed axonal degeneration in the white matter throughout the spinal cord and focal area of brain stem. Central distal spinal axonopathy was diagnosed based on the distribution and quality of the lesions in the proximal and distal spinal cord and the brainstem. There are no reports that concurred with the past pathological characteristics and the present case. Histopathological findings and distribution of the lesions in the present case resembled those of inherited progressive spinal myelopathy in Murray Grey cattle with unknown etiology.</p>

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