A fluorescent chemosensor array for the detection of sulfur-containing amino acids

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  • SASAKI Yui
    東京大学生産技術研究所　物質・環境系部門
  • MINAMI Tsuyoshi
    東京大学生産技術研究所　物質・環境系部門

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  • 含硫アミノ酸の検出を指向した蛍光ケモセンサアレイ
  • ガンリュウアミノサン ノ ケンシュツ オ シコウ シタ ケイコウ ケモセンサアレイ

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Abstract

<p>We herein report a chemosensor array for the detection of sulfur-containing amino acids （SCAAs） that play crucial roles in maintaining the homeostasis of organisms in our bodies. The chemosensor array was fabricated using two offthe-shelf coumarin dyes and a zinc（II） ion, which showed various optical changes by adding SCAAs. With pattern recognition techniques, the chemosensor array succeeded in the simultaneous multi-SCAAs recognition and the quantitative detection of SCAA in human blood serum. We believe that the proposed chemosensor array could be used as an easy-to-handle analytical method for biological samples.</p>

Journal

  • SEISAN KENKYU

    SEISAN KENKYU 73 (3), 179-183, 2021-05-01

    Institute of Industrial Science The University of Tokyo

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