Comprehensive analysis of extracellular vesicle miRNA in urine using nanowire devices and AI, and its application to cancer detection

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  • Yasui Takao
    Graduate School of Engineering, Nagoya University Institutes of Innovation for Future Society, Nagoya University PRESTO, JST
  • Baba Yoshinobu
    Graduate School of Engineering, Nagoya University Institutes of Innovation for Future Society, Nagoya University National Institutes for Quantum and Radiological Science and Technology

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Other Title
  • ナノワイヤデバイスとAIによる尿中細胞外小胞miRNAの網羅的解析とがん検知への展開
  • ナノワイヤデバイス ト AI ニ ヨル ニョウチュウ サイボウ ガイ ショウホウmiRNA ノ モウラテキ カイセキ ト ガン ケンチ エ ノ テンカイ

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Abstract

Liquid biopsy is a method that is expected to be able to detect and track the cancers using blood, urine, saliva and other body fluids. The advantages of liquid biopsy are that it is extremely minimally invasive compared to tissue biopsies, and that it is easy to perform the repeated and frequent tests that are necessary for long-term tracking. Recently, extracellular vesicles （EVs） have been added to the list of biological materials to be analyzed by liquid biopsy. In this paper, we introduce the comprehensive analysis of microRNAs contained in EVs in urine using nanowire devices and AI, and its application to cancer detection.

Journal

  • Drug Delivery System

    Drug Delivery System 36 (2), 124-129, 2021-03-25

    THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM

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