甲状腺全摘出術によって診断されたIgG4関連甲状腺炎例

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  • 阪本 大樹
    関西医科大学香里病院耳鼻咽喉科・頭頸部外科
  • 八木 正夫
    関西医科大学附属病院耳鼻咽喉科・頭頸部外科
  • 岩井 大
    関西医科大学附属病院耳鼻咽喉科・頭頸部外科

書誌事項

タイトル別名
  • A Case of IgG4-related Thyroiditis Diagnosed by Total Thyroidectomy
  • コウジョウセン ゼン テキシュツジュツ ニ ヨッテ シンダン サレタ IgG4 カンレン コウジョウセンエンレイ

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<p>IgG4-related disease (IgG4-RD) mainly manifests as a mass or a nodular lesion with IgG4-positive plasma cell infiltration and fibrosis in multiple organs. Comprehensive diagnostic criteria as well as several organ-specific diagnostic criteria for IgG4-RD have been published. Although there are some case reports of cases of Hashimoto’s disease, Riedel’s thyroiditis and Basedow disease with elevated serum IgG4 levels, these cases have not been categorized clearly.</p><p>We report the case of a 59-year-old woman who presented with a neck swelling and dyspnea breathlessness. Laboratory examination revealed evidence of hypothyroidism, markedly elevated levels of thyroid autoantibodies, and elevated serum IgG4 levels. We performed total thyroidectomy, and histopathological examination of the respected specimen revealed findings consistent with the diagnosis of IgG4 thyroiditis, including IgG4-positive cell infiltration and fibrosis. The serum IgG4 levels returned to within normal range post surgery.</p><p>There is no well-established treatment for IgG4-related thyroiditis until date, and it is necessary to explore effective treatments for IgG4-related thyroiditis.</p>

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