Effect of Magnetic Nanoparticle Internalization on Cell Density in Skeletal Muscle Tissue
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- Kirihara Yuji
- Tokyo Institute of Technology
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- Miyata Hiromu
- Tokyo Institute of Technology
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- Peng Zugui
- Tokyo Institute of Technology
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- Shimba Kenta
- The University of Tokyo
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- Miyamoto Yoshitaka
- National Center for Child Health and Development
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- Shimizu Kazunori
- Nagoya University
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- Honda Hiroyuki
- Nagoya University
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- Yagi Tohru
- Tokyo Institute of Technology
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説明
<p>The engineering of skeletal muscle tissue has gained considerable attention in recent years because of its clinical applications, which include muscle replacement and treatment of muscle-related disease. Magnetic nanoparticle internalization by skeletal muscle cells has been proposed as a means of improving cell density. In this study, by embedding magnetic nanoparticles in mouse C2C12 myoblast cells to engineer a muscle tissue sheet, we evaluated the cellular uptake of magnetic nanoparticles and their effects on cell proliferation and differentiation. Our results show a tendency for decreased muscle fiber thickness in C2C12 cells with internalized magnetite nanoparticles. However, no change was found in the number of cells or differentiation.</p>
収録刊行物
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- 電気学会論文誌Ｃ（電子・情報・システム部門誌）
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電気学会論文誌Ｃ（電子・情報・システム部門誌） 141 (7), 795-801, 2021-07-01
一般社団法人 電気学会
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詳細情報 詳細情報について
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- CRID
- 1390851497214033024
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- NII論文ID
- 130008060387
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- NII書誌ID
- AN10065950
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- ISSN
- 13488155
- 03854221
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- NDL書誌ID
- 031608771
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- 本文言語コード
- en
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- 資料種別
- journal article
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- データソース種別
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- JaLC
- NDLサーチ
- Crossref
- CiNii Articles
- KAKEN
- OpenAIRE
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- 抄録ライセンスフラグ
- 使用不可
