Spontaneous Intrauterine Repairment of Cleft Palate Induced by Amniocentesis in Rats
Bibliographic Information
- Other Title
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- Spontaneous intrauterine repairment of
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Abstract
ABSTRACT On day 15 of gestation, 180 fetal sacs in 43 pregnant Charles Foster rats were subjected to amniocentesis producing a series of total or partial clefts in the hard and soft palate regions. Fetuses recovered on days 19,20 or 21 showed a gradual decline in the incidence of total clefts with increasing gestational age, i.e. 34% on day 19, 29% on day 20 and 13% on day 21, suggesting spontaneous ‘repairment’ of the clefts induced by amniotic sac puncture. Prenatal ‘repairment’ at times leaving residual partial clefts in the hard palate, suggested delayed rotation of the palatine shelves following reaccumulation of lost quantity of amniotic fluid and withdrawal of tongue obstruction. The experiment suggested that the palatine shelves retain intrinsic ‘shelf force’ for a much longer period than thought earlier. However, a gradual increase in the incidence of residual partial cleft with increasing gestational age, i.e. 45% on day 19; 50% on day 20 and 67% on day 21, respectively, suggests only incomplete (partial) repair in most of the cases probably due to paucity of time.
Journal
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- official journal of Congeital Anomalies Research Association of Japan
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official journal of Congeital Anomalies Research Association of Japan 31 (2), 81-88, 1991
The Japanese Teratology Society
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Details 詳細情報について
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- CRID
- 1390851784657893120
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- NII Article ID
- 110002786355
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- NII Book ID
- AN10066760
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- ISSN
- 09143505
- 24331503
- 17414520
- 00372285
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- NDL BIB ID
- 3736404
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- Web Site
- http://id.ndl.go.jp/bib/3736404
- https://ndlsearch.ndl.go.jp/books/R000000004-I3736404
- https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1741-4520.1991.tb00361.x
- https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1741-4520.1991.tb00361.x
- https://search.jamas.or.jp/link/ui/1992026364
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed