A Case of Pulmonary Nocardiosis Caused by <i>Nocardia otitidiscaviarum </i>in which the Causative Bacterium was Identified by MALDI-TOF MS

DOI Web Site 10 References
  • SASAHARA Masayuki
    <sup> </sup>Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine Department of General Medicine, Social Welfare Corporation Hokkaido Social Work Association Obihiro Hospital
  • SAITO Atsushi
    <sup> </sup>Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine
  • MIYASAKA Yuki
    <sup> </sup>Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine
  • HAYASHI Toshihiro
    <sup> </sup>Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine
  • KODAMA Kentaro
    <sup> </sup>Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine
  • HORI Tetsuya
    Department of General Medicine, Social Welfare Corporation Hokkaido Social Work Association Obihiro Hospital

Bibliographic Information

Other Title
  • MALDI-TOF MS を用いて<i>Nocardia otitidiscaviarum </i>を同定した 肺ノカルジア症の1例

Search this article

Description

<p>We report the case of an 88-year-old woman who was admitted with pneumonia. Sputum examination revealed aerobic actinomycetales, and we initiated the patient on therapy with imipenem/cilastatin (IPM/CS). However, the fever persisted, and the radiological findings started to worsen. On day 6 of the illness, N. otitidiscaviarum was identified by MALDI-TOF MS (Matrix As- sisted Laser Desorption Ionization Time of Flight Mass Spectrometry). We changed the antibacterial drug to ST, following which the patient improved. It has been reported that some bacterial species causing pulmonary nocardiosis show natural resistance to certain antibiotics. While not downplaying the significance of culture and drug sensitivity examinations, we suggest that for rare bacterial species, such as in the present case, the application of MALDI-TOF MS for identifying the bacterial species potentially allows early selection of effective therapeutic agents.</p>

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 95 (1), 17-20, 2021-01-20

    The Japanese Association for Infectious Diseases

References(10)*help

See more

Related Projects

See more

Keywords

Details 詳細情報について

Report a problem

Back to top