Genetic toxicity of phosphorylated cellulose nanofibrils

DOI
  • FUJITA Katsuhide
    National Institute of Advanced Industrial Science and Technology (AIST)
  • OBARA Sawae
    National Institute of Advanced Industrial Science and Technology (AIST)
  • MARU Junko
    National Institute of Advanced Industrial Science and Technology (AIST)
  • ENDOH Shigehisa
    National Institute of Advanced Industrial Science and Technology (AIST)

Bibliographic Information

Other Title
  • リン酸エステル化セルロースナノファイバーの遺伝毒性

Abstract

<p>Cellulose nanofibrils (CNFs), also known as cellulose nanofibers, there is a concern about risks of carcinogenicity or mesothelioma. A battery of three commonly used assays, namely Ames test, an in vitro chromosomal aberration test, and a mammalian erythrocyte micronucleus test illustrated that the phosphorylated CNFs examined in this study did not induce genotoxicity. We believe that these results will be useful for predicting the human carcinogenic risk of CNFs and accelerate their industrial application. This study was supported by project grants from the New Energy and Industrial Technology Development Organization (NEDO).</p>

Journal

Details 詳細情報について

  • CRID
    1390851961199621504
  • NII Article ID
    130008073721
  • DOI
    10.14869/toxpt.48.1.0_p-30
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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