A Case of Neuroendocrine Carcinoma of the Breast

DOI Web Site Web Site Web Site 10 References Open Access

Bibliographic Information

Other Title
  • 乳腺原発低分化神経内分泌癌の１例
  • ニュウセン ゲンパツ テイブンカ シンケイ ナイブンピツ ガン ノ 1レイ
  • 症例報告 乳腺原発低分化神経内分泌癌の1例
  • ショウレイ ホウコク ニュウセン ゲンパツ テイブンカ シンケイ ナイブンピガン ノ 1レイ

Search this article

Abstract

<p>We herein report an experience of neuroendocrine carcinoma of the breast. A 73-year-old woman visited our hospital because of a tumor of the left breast. The tumor was diagnosed as category 3 by mammography. Ultrasonography diagnosed as 16mm size in diameter with relative clear margin in D area in the left breast. Imaging of MRI showed the tumor had early enhancement following gradual decreasing. PET displayed a slight accumulation of FDG on the tumor. Biopsy of the tumor was diagnosed as invasive carcinoma histologically. We performed partial mastectomy of left breast and sentinel lymph node biopsy. Tumor cells were demonstrated having formation of　Rosset and pseudo-Rosset in perivascular lesion histopathologically. Tumor cells were displayed as positive of Chromogranin A stain, positive of NSE stain, slight positive of CD56 stain, and positive of Synaptophysin stain immune-pathologically. The tumor was made a definite diagnosis as poorly differentiated neuroendocrine carcinoma having many mitotic figures and strong cellular atypia. After surgery the patient received radiation therapy and has been under follow-up observations with medication of aromatase inhibitor. Generally atypical carcinoid is said to be high grade of malignancy, so this case should be under careful observation in a long-term.</p>

Journal

References(10)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top