Study on Phase Transitions of Phospholipid Bilayer Membranes under High Pressure

  • MATSUKI Hitoshi
    Graduate School of Technology, Industrial and Social Sciences, Tokushima University

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  • 高圧力下におけるリン脂質二重膜相転移の研究
  • 高圧力下におけるリン脂質二重膜相転移の研究 : 高圧力学会学会賞
  • コウアツリョク カ ニ オケル リン シシツ ニジュウマクソウ テンイ ノ ケンキュウ : コウアツリョク ガッカイ ガッカイショウ

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Abstract

<p>We have begun to study phase transitions of phospholipid bilayer membranes under high pressure from the most representative model-membrane phospholipid, dipalmitoylphosphatidylcholine (DPPC), early in the 1990s and accumulated many bilayer phase diagrams of various kinds of phospholipids depending on pressure and temperature until now. In this review, the comprehensive study on the phospholipid bilayer membranes under high pressure based on the temperature and pressure phase diagrams is described and the correlation among thermodynamic variables, lipid molecular structures and membrane states is explained.</p>

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