A case of huge neurofibroma arising in the palate of a patient with neurofibromatosis type I

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  • NAKAMA Jyouji
    Department of Dentistry, Oral and Maxillofacial Surgery, Okinawa Yaeyama Hospital
  • KANO Takeshi
    Department of Dentistry, Oral and Maxillofacial Surgery, Okinawa Miyako Hospital
  • HIGA Tsutomu
    Department of Dentistry, Oral and Maxillofacial Surgery, Okinawa Prefectural Nanbu Medical Center & Children’s Medical Center
  • MEKARU Yasuaki
    Department of Dentistry, Oral and Maxillofacial Surgery, Okinawa Chubu Hospital
  • HIGA Moritoshi
    Department of Dentistry, Oral and Maxillofacial Surgery, Okinawa Prefectural Nanbu Medical Center & Children’s Medical Center
  • ARAKAKI Keiichi
    Department of Dentistry, Oral and Maxillofacial Surgery, Okinawa Chubu Hospital

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  • 神経線維腫症1型患者の口蓋に発生した巨大な神経線維腫の1例
  • シンケイ センイ シュショウ 1ガタ カンジャ ノ コウガイ ニ ハッセイ シタ キョダイ ナ シンケイ センイ シュ ノ 1レイ

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Abstract

<p>Neurofibromatosis type I (NF1) is a chromosomal dominant hereditary disease characterized by cafe-au-lait spots of the skin and multiple neurofibroma. Oral manifestation of NF1 is relatively infrequent. We report a rare case of huge neurofibroma arising in the palate, associated with NF1. A 39-year-old woman visited our department with the complaint of a painless mass in the hard palate. An elastic-soft swelling measuring 50 x 38 mm was found on the right palate. The tumor was excised under general anesthesia. Histopathological findings revealed neurofibroma. The tumor has not recurred, and the patient has made good progress.</p>

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