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Antigenemia monitoring of Cytomegalovirus in ICU: a single center retrospective study
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- Baba Ayaka
- Department of Emergency and Critical Care Medicine, Chiba University Graduate School of Medicine
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- Takahashi Nozomi
- Department of Emergency and Critical Care Medicine, Chiba University Graduate School of Medicine
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- Takeda Masahiko
- Department of Emergency and Critical Care Medicine, Chiba University Graduate School of Medicine
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- Oda Shigeto
- Department of Emergency and Critical Care Medicine, Chiba University Graduate School of Medicine Department of Emergency Medicine, Chiba Kaihin Municipal Hospital
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- Nakada Taka-aki
- Department of Emergency and Critical Care Medicine, Chiba University Graduate School of Medicine
Bibliographic Information
- Other Title
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- 集中治療室におけるサイトメガロウイルス抗原血症検査に関する検討：単施設後方視的研究
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Description
<p>Introduction: Cytomegalovirus (CMV) infection is associated with increased length of hospital stay and mortality in critically ill patients. We evaluated the efficacy of periodic monitoring of CMV antigenemia in intensive care units (ICU). Methods: During the four-year study period, CMV antigenemia tests were conducted in 341 cases. The tests were ordered by the attending physician’s decisions during the first two years (Before group), and conducted periodically once a week in the latter two years (After group). The primary outcome was the number of patients with positive antigenemia. Secondary outcomes were the number of positive cells, the duration of antiviral drug administration. Results: The number of patients with positive CMV antigenemia was significantly higher (3.75 times) in the After group than the Before group (P＜0.0001). Patients had a significantly shorter duration of antiviral drug administration in the After group than the Before group. Conclusions: Periodic monitoring of CMV antigenemia in the ICU revealed more patients with positive tests and shortened antiviral drug administration.</p>
Journal
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- Journal of the Japanese Society of Intensive Care Medicine
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Journal of the Japanese Society of Intensive Care Medicine 29 (1), 3-7, 2022-01-01
The Japanese Society of Intensive Care Medicine
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Details 詳細情報について
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- CRID
- 1390853567321255808
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- NII Article ID
- 130008138885
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- ISSN
- 1882966X
- 13407988
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
- OpenAIRE
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- Abstract License Flag
- Disallowed
