Deep and Durable Response After Discontinuation of Nivolumab/Ipilimumab Combination Therapy for Metastatic Renal Cell Carcinoma : A Case Report

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  • Tsuruta Masafumi
    The Department of Urology, Ohara Health Care Foundation Kurashiki Central Hospital
  • Shibasaki Noboru
    The Department of Urology, Ohara Health Care Foundation Kurashiki Central Hospital
  • Iguch Ryo
    The Department of Urology, Ohara Health Care Foundation Kurashiki Central Hospital
  • Yamaguchi Takahiro
    The Department of Urology, Ohara Health Care Foundation Kurashiki Central Hospital
  • Ota Hideto
    The Department of Urology, Ohara Health Care Foundation Kurashiki Central Hospital
  • Fuchigami Yasushi
    The Department of Urology, Ohara Health Care Foundation Kurashiki Central Hospital
  • Magaribuchi Toshihiro
    The Department of Urology, Ohara Health Care Foundation Kurashiki Central Hospital
  • Naito Hirohito
    The Department of Urology, Ohara Health Care Foundation Kurashiki Central Hospital
  • Terai Akito
    The Department of Urology, Ohara Health Care Foundation Kurashiki Central Hospital

Bibliographic Information

Other Title
  • Nivolumab/Ipilimumab 併用療法を施行し治療中止後も良好な治療効果の継続を認めた進行性腎癌の1例
  • Nivolumab/Ipilimumab ヘイヨウ リョウホウ オ シコウ シ チリョウ チュウシ ゴ モ リョウコウ ナ チリョウ コウカ ノ ケイゾク オ ミトメタ シンコウセイジンガン ノ 1レイ

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Description

A 47-year-old man was referred to our hospital for epigastric pain and cough, and was given a diagnosis of left clear cell renal carcnoma with multiple pulmonary metastases based on the results of renal tumor biopsy (cT3aN0M1). He received nivolumab/ipilimumab combination therapy, but developed diarrhea (grade 3) on day71, and treatment was discontinued. However, a deep and durable response after discontinuation of treatment was shown, and we were able to perform nephrectomy on day336. He is undergoing nivolumab therapy for pulmonary metastases.

Journal

  • 泌尿器科紀要

    泌尿器科紀要 66 (12), 443-448, 2020-12-31

    泌尿器科紀要刊行会

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