Usefulness of microbubble test by transthoracic echocardiography

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  • TAKAHASHI Keita
    Department of Clinical Functional Physiology, Toho University Ohashi Medical Center
  • YOSHIKAWA Koichi
    Department of Clinical Functional Physiology, Toho University Ohashi Medical Center
  • FUJISAKI Jun
    Department of Clinical Functional Physiology, Toho University Ohashi Medical Center
  • MAETANI Iruru
    Department of Clinical Functional Physiology, Toho University Ohashi Medical Center
  • HAYAMA Hiromasa
    Department of Cardiology, Toho University Ohashi Medical Center
  • MAKINO Kenji
    Department of Cardiology, Toho University Ohashi Medical Center
  • HASHIMOTO Go
    Department of Cardiology, Toho University Ohashi Medical Center
  • UCHI Takafumi
    Department of Neurology, Toho University Ohashi Medical Center
  • KIHARA Hideo
    Department of Neurology, Toho University Ohashi Medical Center
  • IWABUCHI Satoshi
    Department of Neurosurgery, Toho University Ohashi Medical Center

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Other Title
  • 経胸壁心臓超音波検査によるマイクロバブルテストの有用性

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Abstract

Patent foramen ovale (PFO) is associated with cerebral embolism of unknown embolic source and migraine, and recently, percutaneous catheter closure has been performed. PFO is confirmed by color Doppler echocardiography as a short-circuiting blood flow signal across atrial septum. However, PFO remains closed at rest in most cases, and color Doppler may not be able to visualize the short-circuiting blood flow. Transesophageal echocardiography (TEE) microbubble test is usually used to detect PFO. However, TEE is an invasive procedure, and the insertion of the probe interferes with adequate Valsalva stress. In this study, we investigated the diagnostic accuracy of PFO in noninvasive transthoracic echocardiography (TTE) microbubble tests. Forty-seven patients (29 males and 18 females, mean age 66.3 years) underwent simultaneous TTE and TEE microbubble tests between July 2018 and December 2019. Results showed that 44 patients (93.6%) had concordant microbubble test determinations of TTE and TEE. Microbubble test by TTE was a useful screening test for the diagnosis of PFO.

Journal

  • Neurosonology

    Neurosonology 34 (3), 153-157, 2021

    The Japan Academy of Neurosonology

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