A patient with chronic hepatitis B who developed hepatocellular carcinoma with hypervascularity in 9 years of close follow-up

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  • Kosaka Masanari
    Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University
  • Kawaoka Tomokazu
    Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University
  • Johira Yusuke
    Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University
  • Shirane Yuki
    Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University
  • Miura Ryoichi
    Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University
  • Murakami Serami
    Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University
  • Yano Shigeki
    Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University
  • Amioka Kei
    Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University
  • Naruto Kensuke
    Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University
  • Andou Yuuwa
    Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University
  • Kosaka Yumi
    Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University
  • Kodama Kenichiro
    Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University
  • Uchikawa Sinsuke
    Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University
  • Fujino Hatsue
    Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University
  • Oono Atsushi
    Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University
  • Nakahara Takashi
    Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University
  • Murakami Eisuke
    Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University
  • Yamauchi Masami
    Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University
  • Imamura Michio
    Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University
  • Kuroda Shintaro
    Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University
  • Kobayashi Tsuyoshi
    Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University
  • Ohdan Hideki
    Department of Gastroenterological and Transplant Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University
  • Nakamura Yuko
    Department of Diagnostic Radiology, Graduate School of Biomedical and Health Sciences, Hiroshima University
  • Awai Kazuo
    Department of Diagnostic Radiology, Graduate School of Biomedical and Health Sciences, Hiroshima University
  • Kido Aya
    Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University
  • Sentani Kazuhiro
    Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University
  • Oue Naohide
    Molecular Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University
  • Arihiro Koji
    Department of Anatomical Pathology, Graduate School of Biomedical and Health Sciences, Hiroshima University
  • Aikata Hiroshi
    Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University

Bibliographic Information

Other Title
  • B型慢性肝炎患者に合併した乏血性結節を画像フォローアップ中に9年目で多血化を呈した肝細胞癌の1例
  • Bガタ マンセイ カンエン カンジャ ニ ガッペイ シタ ボウケツセイ ケッセツ オ ガゾウ フォローアップ チュウ ニ 9ネンメ デ タケツカ オ テイシタ カン サイボウ ガン ノ 1レイ

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Abstract

<p>A 40-year-old woman received interferon and entecavir treatment for hepatitis B since October 20XX. The HBV DNA level was negative.</p><p>In 20XX, contrast-enhanced magnetic resonance imaging (MRI) showed a tumor, approximately 10 mm in size, in the liver S6, with a low signal in the hepatocellular contrast phase but no contrast effect in the arterial predominant phase.</p><p>The patient was followed with contrast-enhanced MRI every 6 months, but there was no change in imaging findings or elevation of tumor marker levels for approximately 9 years.</p><p>In 20XX+9 years, faint staining appeared in the arterial predominant phase of the contrast-enhanced MRI, but there was no increase in the tumor marker levels.</p><p>Because hypervascularized hepatocellular carcinoma was suspected, hepatic subsegmentectomy was performed in 20XX+10 years. The patient was diagnosed with moderately differentiated hepatocellular carcinoma.</p><p>We present a case of a patient in whom a hypovascular tumor was unchanged for a long time, but hypervascularity was noted after 9 years.</p>

Journal

  • Kanzo

    Kanzo 63 (1), 24-34, 2022-01-01

    The Japan Society of Hepatology

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