A Case of Type 4 Gastric Cancer with Peritoneal Dissemination in which a Pathological Complete Response was Obtained by SOX(S-1/L-OHP)Therapy
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- NAKAI Tomoki
- Second Department of Surgery, Wakayama Medical University
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- NAKAMURA Masaki
- Second Department of Surgery, Wakayama Medical University
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- OJIMA Toshiyasu
- Second Department of Surgery, Wakayama Medical University
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- HAYATA Keiji
- Second Department of Surgery, Wakayama Medical University
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- TAKEUCHI Akihiro
- Second Department of Surgery, Wakayama Medical University
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- WARIGAYA Takeshi
- Department of Pathology, Wakayama Medical University
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- MIKASA Yurina
- Department of Pathology, Wakayama Medical University
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- YAMAUE Hiroki
- Second Department of Surgery, Wakayama Medical University
Bibliographic Information
- Other Title
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- SOX療法によりpCRが得られた腹膜播種を伴う4型胃癌の1例
- SOX リョウホウ ニ ヨリ pCR ガ エラレタ フクマク ハシュ オ トモナウ 4ガタ イガン ノ 1レイ
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Abstract
<p>A 65-year-old woman presented to our hospital with a high CEA level. Esophagogastroduodenoscopy showed Type 4 advanced gastric cancer extending from the upper body of the stomach to the angular region. Biopsy examination showed a moderately to poorly differentiated adenocarcinoma. On staging laparoscopy, peritoneal lavage cytology was positive, and peritoneal dissemination was found. The clinical stage was T4aN2M1 (PER) : Stage IVB. After five courses of SOX (S-1/L-OHP) were administered, the primary tumor and enlarged lymph nodes had shrunk, and the second-look staging laparoscopy was performed. Since peritoneal dissemination and cytology became negative, conversion surgery (laparoscopic total gastrectomy with D2 lymph node dissection) was performed. Histopathological examination showed that the tumor component in the primary tumor and the lymph nodes had disappeared. Histological effectiveness was Grade 3 (pathological complete response). The patient was discharged without postoperative complications. The patient has received S-1 as postoperative adjuvant chemotherapy and has had no recurrence 10 months after the operation.</p>
Journal
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- Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)
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Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 82 (7), 1327-1333, 2021
Japan Surgical Association
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Details 詳細情報について
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- CRID
- 1390853879745723392
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- NII Article ID
- 130008149220
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- NII Book ID
- AA11189709
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- ISSN
- 18825133
- 13452843
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- NDL BIB ID
- 031639245
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed