The effectiveness of emergency hemodialysis for the treatment of hypermagnesemia

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  • 高マグネシウム血症に対する緊急血液透析の治療効果
  • コウマグネシウム ケッショウ ニ タイスル キンキュウ ケツエキ トウセキ ノ チリョウ コウカ

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<p>【Aims】The effect of hemodialysis (HD) for hypermagnesemia was examined. 【Methods】We retrospectively analyzed nine patients who underwent emergency HD for hypermagnesemia at our hospital. 【Results】The median age was 76 (range: 59–87), including four males and five females. The symptoms were consciousness disturbance, blood pressure decrease, and bradycardia. The median serum Mg value was 6.0 (3.7–8.1) mg/dL, and the serum Cre value was 4.31 (0.62–9.93)mg/dL before HD. HD was performed for 2–4 hours at a blood flow rate of 80–120mL/min. After HD, the serum Mg value decreased 4.4 (2.9–5.6) mg/dL by 26.7 (17.9–41.2)%, with symptoms improving in all cases. Seven patients had elevated serum Mg values on the morning after HD compared to those values measured just at the end of HD, and the rate of elevation was 7.1 (2.0–18.2)%. These patients tended to show a lower eGFR before HD compared to the eGFR values of those who did not have elevated serum Mg values. 【Conclusion】HD for hypermagnesemia is thus considered to be an effective treatment modality for reducing the serum Mg values and achieving a rapid improvement in the symptoms, however, close attention must be paid to the occurrence of rebound phenomenon.</p>

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