<p>Abstract : Purpose : The purpose of this study was to evaluate the flow of root canal sealers including a new tricalcium silicate-based sealer and to verify its compliance to ISO 6876 (2012).</p><p> Materials and Methods : Two kinds of calcium silicate-based sealer (Bio-C^® SEALER, Well-Pulp ST^®), a bioactive glass-based sealer (Canal Sealer BG^®), an epoxy resin sealer (AH plus JET^®) and a zinc oxide eugenol sealer (NISHIKA CANAL SEALER, Control) were prepared. After manipulation of the sealer, 0.05 mL of the material was placed in the center of a glass plate using a graduated disposable syringe (n=10). Another glass plate (20 g) was placed over the sealer, and a 100-g weight was put on the plate and kept there for 10 minutes. After this period, the longest diameter and shortest diameter of the resulting sealer disks were measured using digital calipers, and the mean value was recorded. The data were analyzed statistically by one-way analysis of variance, followed by Tukey-Kramer multiple tests.</p><p> Results and Discussion : Bio-C^® SEALER showed the highest flow, and Canal Sealer BG^® showed the lowest flow in the analysis. In a comparison of flow values among bio-ceramic sealers, Canal Sealer BG^® presented a flow significantly lower than Bio-C^® SEALER and Well-Pulp ST^® (p<0.01). Also, Canal Sealer BG^® presented a flow significantly lower than AH Plus JET^® (p<0.05). Calcium silicate-based endodontic sealers showed higher flow values than any other sealers.</p><p> Conclusion : Flow is an important property for root canal filling and to facilitate obturation. Single-cone techniques rely on a sealer to flow and fill any space between the cone and dentin to provide a tight seal. Premixed ready-to-use calcium silicate-based endodontic sealers presented high flow values within the limitations of this study, and their superior flowability may be beneficial in single-cone root-filling techniques.</p>