Effects of negative ions on wound healing in normal and Akita diabetic mice
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- Mawaki Ayana
- Department of Nursing Sciences, School of Health Sciences, Graduate School of Medicine, Nagoya University
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- Iswara Arya
- Graduate Course of Nursing Science, Division of Health Sciences, Graduate School of Medical Sciences, Kanazawa University
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- Mukai Kanae
- Department of Nursing Sciences, Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University
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- Nakajima Yukari
- Department of Nursing Sciences, Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University
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- Nakatani Toshio
- Department of Nursing Sciences, Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University
Bibliographic Information
- Other Title
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- マイナスイオンの正常とAkita糖尿病マウスの皮膚創傷治癒への効果
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Abstract
<p>Negative ions exert various effects. The present study investigated whether negative ions from a negative potential therapy device affect skin wound healing in normal mice (Experiment 1) and Akita diabetic mice (Experiment 2). Two circular skin wounds of 8 mm in diameter were created on the right and left sides of the backs of mice, which were divided into two groups: a negative ion exposure group and non-exposure group. In experiment 1, wound properties were examined under an optical microscope. The results obtained showed a similar healing process in both groups, with no significant differences in wound area reductions. Furthermore, no significant differences were noted in wound area reductions between the two groups in experiment 2. On day 10 after wounding in experiment 1 and on day 13 in experiment 2, the wound area had decreased to approximately 20% of the original wound area. Among the histological findings obtained in experiment 1, no significant differences were observed in angiogenesis or collagen fiber development between the two groups. Therefore, the efficacy of negative ions for promoting skin wound healing remains unclear.</p>
Journal
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- Structure and Function
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Structure and Function 20 (2), 69-75, 2022
Co-medical Research Society of Structure and Function
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Details 詳細情報について
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- CRID
- 1390854117435733760
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- NII Article ID
- 130008163114
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- ISSN
- 18846084
- 13477145
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed