A case of radicular cyst exhibiting verrucous proliferation of the lining epithelium

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  • TAKAHATA Sosuke
    Department of Dentistry and Oral Surgery, Kinki Central Hospital The 1st Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University
  • ISHII Shoichiro
    Department of Dentistry and Oral Surgery, Kinki Central Hospital
  • YAKUSHIJI Noboru
    Department of Dentistry and Oral Surgery, Kinki Central Hospital
  • KOGO Mikihiko
    The 1st Department of Oral and Maxillofacial Surgery, Graduate School of Dentistry, Osaka University

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  • 裏層上皮の疣贅状増殖を呈した歯根囊胞の1例
  • リソウ ジョウヒ ノ ユウゼイジョウ ゾウショク オ テイシタ シコンノウホウ ノ 1レイ

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Abstract

<p>Verrucous carcinoma arising from an odontogenic cyst is extremely rare. We report a case of radicular cyst exhibiting verrucous proliferation of the lining epithelium, which resembles verrucous carcinoma of the oral mucosa. Panoramic radiographs showed a well-defined radiolucent lesion surrounding the root of the left maxillary first molar. The clinical diagnosis was radicular cyst. The cyst was surgically removed, and the left maxillary first molar was extracted. Histopathological examination revealed a cystic structure consisting of dense fibrous connective tissue, and most of the luminal surface was covered with stratified squamous epithelium with marked thickening and hyperkeratosis. The squamous epithelium had an acute angular spire-like shape in some areas, while the basal layer showed nuclear enlargement and nuclear fission, but the atypia was not so obvious and there was no obvious invasive growth into the wall. The lesion was diagnosed as a radicular cyst exhibiting verrucous proliferation of the lining epithelium. No recurrence and metastasis have been observed to date.</p>

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