Calculation of cut-off value of carbohydrate deficiency transferrin ratio in Japanese in medical examination business: Cut-off value to detect daily drinking habits

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  • TSURU Kano
    Department of Clinical Laboratory, Saiseikai Imabari Hospital
  • AKAO Tomohiro
    Department of Clinical Laboratory, Saiseikai Imabari Hospital
  • KUWABARA Yukima
    Department of Clinical Laboratory, Saiseikai Imabari Hospital
  • FUTAMI Mutsumi
    Department of Clinical Laboratory, Saiseikai Imabari Hospital
  • SHIGYOU Nami
    Department of Clinical Laboratory, Saiseikai Imabari Hospital
  • YAMAMOTO Shinji
    Department of Clinical Laboratory, Saiseikai Imabari Hospital
  • MORITA Ayumi
    Department of Clinical Laboratory, Saiseikai Imabari Hospital

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Other Title
  • 健診事業における日本人の糖鎖欠損トランスフェリン比率のカットオフ値の算出―毎日の習慣飲酒者を検出するためのカットオフ値―
  • ケンシン ジギョウ ニ オケル ニホンジン ノ トウサ ケッソン トランスフェリン ヒリツ ノ カットオフチ ノ サンシュツ : マイニチ ノ シュウカン インシュシャ オ ケンシュツ スル タメ ノ カットオフチ

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Abstract

<p>Recently, it has been reported that the ratio of carbohydrate deficiency transferrin (%CDT) present in transferrin is useful as a marker of alcohol consumpstion. In general, Japanese people tend to drink less alcohol than Westerners. Therefore, it is necessary to examine the cutoff value, but there are few reports on this issue. We examined the Japanese cut-off value of %CDT in the detection of daily drinking habits in the medical examination business. The subjects were 234 patients who visited our medical examination center in February 2018. The questionnaire was used to classify 74 patients into the nondrinking group, 80 patients into the occasionally drinking group, and 80 patients into the daily drinking group. As a result of the examination, we found that the cut-off value for identifying a habitual drinker, that is, one who drinks daily, was 1.96%, the sensitivity was 18.8%, and the specificity was 95.0%.</p>

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