Feature of “<i>qi</i>, Blood, Fluid” Factors in Patients with Sjögrenʼs Syndrome : In Comparison with Patients of Rheumatoid Arthritis in Remission

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  • ABE Takeo
    Division of Diabetes, Endocrinology and Clinical Immunology, Department of Internal Medicine, Hyogo College of Medi­cine Department of Rheumatology Medicine, Kobe City Medical Center West Hospital
  • TAMURA Masao
    Division of Diabetes, Endocrinology and Clinical Immunology, Department of Internal Medicine, Hyogo College of Medi­cine Department of Rheumatology Medicine, Kobe City Medical Center West Hospital
  • OH Koji
    Department of General Internal Medicine, Kobe City Medical Center West Hospital
  • FUJIWARA Hiroyuki
    Department of Orthopedic surgery, Kobe City Medical Center West Hospital

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Other Title
  • シェーグレン症候群患者における気血水の傾向
  • シェーグレン症候群患者における気血水の傾向 : 寛解状態の関節リウマチ患者との比較
  • シェーグレン ショウコウグン カンジャ ニ オケル キケツスイ ノ ケイコウ : カンゲジョウタイ ノ カンセツ リウマチ カンジャ ト ノ ヒカク
  • ～寛解状態の関節リウマチ患者との比較～

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Abstract

<p>To determine the body constituents patterns comprised of “qi, blood, fluid” factors associated with oral health-­related QOL (OHRQOL) of patients with Sjögren's syndrome (SS), 41 SS patients and 32 RA patients in remission were enrolled. The body constituents patterns were measured by using Terasawa's “qi, blood, fluid” score, and the simple version of yin deficiency questionnaire (yin-­deficiency score). OHRQOL were evaluated using the oral health impact profile (OHIP-­14). In the first study, the body constituents pattern scores were compared between SS group and RA (in remission) group, using the univariate and multivariate analysis. In the second study, the association between OHIP­14 and the body constituents pattern scores was analyzed. In the first study, all the scores were significantly higher in SS group, and the multivariable logistic regression identified yin deficiency (p = 0.02) and blood stasis (p = 0.01) as the significantly associated factors with SS group. In the second study, all the scores, except for the blood stasis pattern, showed positive correlation with OHIP-­14. The multiple regression analysis identified qi stagnation (p = 0.003) as the significantly associated factors with OHIP­-14. This study revealed that yin deficiency and blood stasis are the significant body constituent patterns in SS patients. In the low OHRQOL cases, qi stagnation should be taken into consideration.</p>

Journal

  • Kampo Medicine

    Kampo Medicine 72 (3), 227-234, 2021

    The Japan Society for Oriental Medicine

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