Observational Study of Local Recurrence after Skin-Sparing Mastectomy or Nipple-Sparing Mastectomy Followed by Immediate Reconstruction in Breast Cancer Patients

DOI
  • Yamamoto Shinya
    Department of Breast and Thyroid Surgery, Yokohama City University Medical Center
  • Narui Kazutaka
    Department of Breast and Thyroid Surgery, Yokohama City University Medical Center
  • Tsunoda Yui
    Department of Plastic Surgery, Yokohama City University Medical Center
  • Muto Mayu
    Department of Plastic Surgery, Yokohama City University Medical Center
  • Satake Toshihiko
    Department of Plastic Surgery, Yokohama City University Medical Center Department of Plastic, Reconstructive and Aesthetic Surgery, Toyama University Hospital
  • Yamada Akimitsu
    Department of Breast and Thyroid Surgery, Yokohama City University Medical Center Department of Gastroenterological Surgery, Yokohama City University School of Medicine
  • Ishikawa Takashi
    Department of Breast and Thyroid Surgery, Yokohama City University Medical Center Department of Breast Surgery and Oncology, Tokyo Medical University
  • Endo Itaru
    Department of Gastroenterological Surgery, Yokohama City University School of Medicine

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Other Title
  • 皮膚温存乳房全切除術または乳頭乳輪温存乳房全切除術における一次再建後の局所再発の検討

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<p>There are still many research gaps regarding local recurrence after skin-sparing mastectomy (SSM) or nipple-sparing mastectomy (NSM) in Japan. Therefore, we retrospectively examined local recurrence in 408 patients who underwent SSM or NSM with immediate reconstruction for primary breast cancer at our hospital. With a median observation period of 73 months, local recurrence was observed in 18 cases, and the estimated 10-year local recurrence rate was 8.2%. The most common local recurrence site was the cutaneous side of the reconstructed breast, observed in eight cases. Local recurrence was most commonly detected because of the patient's awareness of the mass (observed in seven cases) or via ultrasound (observed in four cases) . Of the locally recurrent cases, four were unresectable and were administered drug therapy, while 14 were resectable and involved surgery. Three of the 14 patients had their reconstructed breasts resected. Of the resectable cases, four required chemotherapy due to local recurrence ; of the resected cases, four involved relapse, and three had distant metastases. The 5-year recurrence-free survival for 14 recurrent and resectable cases was 47.2%. The prognosis for patients with local recurrence was poor.</p>

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