Conditioned Taste Aversion to L-Amino Acid Taste Stimuli and Oral Transcriptional Changes to Type 1 Taste Receptors T1R1 and T1R3 on Chronic Exposure to L-Alanine Solution in Chickens
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- Yoshida Yuta
- Department of Food and Life Sciences, College of Agriculture, Ibaraki University
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- Tanaka Ryota
- Laboratory of Functional Anatomy, Faculty of Agriculture, Kyushu University
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- Fujishiro Shu
- Department of Food and Life Sciences, College of Agriculture, Ibaraki University
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- Nishimura Shotaro
- Laboratory of Functional Anatomy, Faculty of Agriculture, Kyushu University
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- Tabata Shoji
- Laboratory of Functional Anatomy, Faculty of Agriculture, Kyushu University
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- Kawabata Fuminori
- Faculty of Agriculture and Life Science, Hirosaki University
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Description
<p>Elucidating taste sensing systems in chickens is an important step toward understanding poultry nutrition. Amino acid taste receptors, type 1 taste receptors 1 and 3 (T1R1 and T1R3, respectively), are expressed in chicken taste cells, and chicken T1R1/T1R3 is activated by L-alanine (L-Ala) and L-serine (L-Ser), but not by L-proline (L-Pro). However, it is not clear whether chickens have a gustatory perception of L-amino acids. Here, we found that chickens conditioned to avoid either L-Ala, L-Ser, or L-Pro solutions could successfully learn to avoid the corresponding L-amino acid solution in the conditioned taste aversion (CTA) test. Because CTA is a well-established learning paradigm generated specifically by pairing gustatory perception and gastrointestinal malaise, the present study suggests that chickens can sense L-amino acids by gustatory perception. In addition, we found that the expression of the T1R1 and T1R3 genes was significantly downregulated in response to chronic exposure to L-Ala solution, but not to acute oral stimulation. Taken together, the present study suggests that chickens have a gustatory perception of L-amino acids, and the expression of T1R1/T1R3 mRNAs in the oral cavity can be regulated by L-amino acid intake. Since chickens can detect L-Pro solutions, additional amino acid receptors, other than T1R1/T1R3, may be involved in L-amino acid taste detection in chickens.</p>
Journal
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- The Journal of Poultry Science
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The Journal of Poultry Science 59 (4), 348-356, 2022
Japan Poultry Science Association
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Keywords
Details 詳細情報について
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- CRID
- 1390856815742319232
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- NII Book ID
- AA11564513
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- ISSN
- 13490486
- 13467395
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- NDL BIB ID
- 032445157
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- KAKEN
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- Abstract License Flag
- Disallowed