Clinical epidemiology and pharmacoepidemiology studies with real-world databases

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  • YOSHIDA Satomi
    Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University
  • TAKEUCHI Masato
    Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University
  • TANAKA-MIZUNO Sachiko
    Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University
  • MIZUNO Kayoko
    Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University
  • NAKASHIMA Masayuki
    Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University
  • FUKASAWA Toshiki
    Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University
  • KAWAKAMI Koji
    Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University

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<p>Hospital-based registry data, including patients’ information collected by academic societies or government based research groups, were previously used for clinical research in Japan. Now, real-world data routinely obtained in healthcare settings are being used in clinical epidemiology and pharmacoepidemiology. Real-world data include a database of claims originating from health insurance associations for reimbursement of medical fees, diagnosis procedure combinations databases for acute inpatient care in hospitals, a drug prescription database, and electronic medical records, including patients’ medical information obtained by doctors, derived from electronic records of hospitals. In the past ten years, much evidence of clinical epidemiology and pharmacoepidemiology studies using real-world data has been accumulated. The purpose of this review was to introduce clinical epidemiology and pharmacoepidemiology approaches and studies using real-world data in Japan.</p>

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