Effect of Residual Volume in a Three-way Stopper and a Syringe on Actual Dose of Radiopharmaceuticals: Effect of Different Three-way Stoppers and Washing

Tsunou Kazutoshi, Ota Shoya

doi:10.6009/jjrt.2022-1259

Bibliographic Information

Other Title

放射性医薬品の実投与量に三方活栓とシリンジ内の残存量が及ぼす影響—異なる三方活栓と共洗いの効果—
放射性医薬品の実投与量に三方活栓とシリンジ内の残存量が及ぼす影響 : 異なる三方活栓と共洗いの効果
ホウシャセイイヤクヒンノジツトウヨリョウニサンボウカッセントシリンジナイノザンソンリョウガオヨボスエイキョウ : コトナルサンボウカッセントキョウアライノコウカ

Search this article

Abstract

<p>The purpose of this study were to evaluate the residual volume of radiopharmaceuticals in the three-way stopper and syringe used during radiopharmaceutical administration and the effect of washing. The three-way stoppers were a top injector tube, a top three-way stopper, and a Nipro three-way stopper with a needle. Sodium pertechnetate [^99mTc] injection (^99mTcO₄⁻) was used to compare the residual volume of radiopharmaceuticals in the three-way stopper and syringe without and with washing. Clinically, 137 patients who underwent cerebral blood flow scintigraphy, dopamine transporter scintigraphy, and bone scintigraphy were included. N-isopropyl-p-[¹²³I]iodoamphetamine (¹²³I-IMP), ¹²³I-N-ω-fluoropropyl-2β-carboxymethoxy-3β-(4-iodophenyl)nortropane (¹²³I-FP-CIT), and ^99mTc-methylene diphosphonate (^99mTc-MDP) were used to compare the residual volume of radiopharmaceuticals in the three-way stopper and syringe without and with washing. The residual volume depended on the type of three-way stopper and radiopharmaceutical used. The residual volume could be reduced by washing, but the effect depended on the type of three-way stopper and radiopharmaceutical used. The residual volume of radiopharmaceuticals in three-way stoppers and syringes can be determined and subtracted to achieve more accurate dose control.</p>

Journal

Japanese Journal of Radiological Technology

Japanese Journal of Radiological Technology 78 (12), 1415-1424, 2022

Japanese Society of Radiological Technology

Keywords

Details 詳細情報について

Export