Efficacy of a Powder Preparation of Sodium Alginate as a Replacement for Alginate Wound Dressing in Endoscopic Sinus Surgery

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  • Sato Yuki
    Department of Otorhinolaryngology, Social Medical Corporation Tenjinkai, Koga Hospital 21 Department of Otorhinolaryngology- Head and Neck Surgery, Saga University Faculty of Medicine
  • Mikuriya Takefumi
    Department of Otorhinolaryngology, Social Medical Corporation Tenjinkai, Koga Hospital 21
  • Tanaka Nariyuki
    Department of Otorhinolaryngology- Head and Neck Surgery, Saga University Faculty of Medicine
  • Takedomi Hirotaka
    Takedomi Clinic
  • Kuratomi Yuichiro
    Department of Otorhinolaryngology- Head and Neck Surgery, Saga University Faculty of Medicine

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  • アルギネート創傷被覆材に代わるESSドレッシング剤　アルギン酸ナトリウム粉末製剤の有用性の検討

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<p>Powder pharmaceutical preparations of the hemostatic agent sodium alginate have been used to promote wound healing in several surgical fields. In endoscopic sinus surgery, calcium alginate dressing has previously been used to promote healing, but this product has been discontinued. We present our initial experience of use of sodium alginate in endoscopic sinus surgery and we compare the use of this product with that of calcium alginate dressing.</p><p>The patients were divided into groups, treated with sodium alginate (n = 39) and calcium alginate (n = 47), with the two groups having similar bleeding volumes and operation times.</p><p>Patients treated with sodium alginate had significantly fewer postoperative hospital visits than those treated with calcium alginate (mean ± SD: 4 ± 0.8 vs. 5 ± 1.5days, p < 0.05), and significantly fewer cases treated with sodium alginate required sinus rinse with Mikulitz maxillary sinus cleaning tube compared to those treated with calcium alginate (0 vs. 6 cases, p < 0.05). These results suggest that sodium alginate is useful and safe for promotion of wound healing in endoscopic sinus surgery, as a replacement for calcium alginate dressing.</p>

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