A case in which CHDF was effective to reperfusion injury by the endovascular treatment to acute limb ischemia

  • Kobori Masashi
    Department of Cardiology, Social Insurance Yokohama Central Hospital
  • Oiwa Koji
    Department of Cardiology, Social Insurance Yokohama Central Hospital
  • Yagi Hideki
    Department of Cardiology, Social Insurance Yokohama Central Hospital
  • Masuoka Keiko
    Department of Cardiology, Social Insurance Yokohama Central Hospital
  • Tomita Makoto
    Department of Cardiology, Social Insurance Yokohama Central Hospital
  • Kanda Koutarou
    Department of Cardiology, Social Insurance Yokohama Central Hospital
  • Kaizu Kazo
    Department of Nephrology, Social Insurance Yokohama Central Hospital
  • Hosokawa Midori
    Department of Nephrology, Social Insurance Yokohama Central Hospital
  • Uto Eisaku
    Department of Nephrology, Social Insurance Yokohama Central Hospital
  • Ishihara Yuko
    Department of Nephrology, Social Insurance Yokohama Central Hospital
  • Takamatu Katuhiro
    Department of medical engineering, Social Insurance Yokohama Central Hospital
  • Watanabe Ayako
    Department of medical engineering, Social Insurance Yokohama Central Hospital
  • Yoshinaka Mari
    Department of medical engineering, Social Insurance Yokohama Central Hospital
  • Kato Tamie
    Department of medical engineering, Social Insurance Yokohama Central Hospital

Bibliographic Information

Other Title
  • 急性下肢虚血(ALI)に対する血管内治療(EVT)による再灌流障害に対してcontinuous hemodiafiltration(CHDF)が有効であった1症例
  • 症例報告 急性下肢虚血(ALI)に対する血管内治療(EVT)による再灌流障害に対してcontinuous hemodiafiltration (CHDF)が有効であった1症例
  • ショウレイ ホウコク キュウセイ カシキョケツ(ALI)ニ タイスル ケッカン ナイ チリョウ(EVT)ニ ヨル サイカンリュウ ショウガイ ニ タイシテ continuous hemodiafiltration (CHDF)ガ ユウコウ デ アッタ 1 ショウレイ

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<p>An 80-year-old male who had undergone repeated leg artery bypass surgery for obstructive arteriosclerosis (ASO) at another hospital developed sharp pain in his left leg, an ulcer, and degenerating gangrene consulted our hospital. We diagnosed acute limb ischemia (ALI) based on palpation and a blood flow evaluation inspection, and performed endovascular treatment (EVT). However, the development of symptoms of ischemia reperfusion injury (myonephropathic metabolic syndrome: MNMS) after revascularization was expected because of the large size of the ischemic region. For this reason, we enforced CHDF (continuous hemodiafiltration) beginning immediately after the procedure as a preventive measure. Although amputation of the lower extremity was necessary due to poor wound healing and sharp pain in the ischemia limb below the Popliteal artery after revascularization, we were able to save the patient’s life without MNMS developing. MNMS is a serious condition that, once it develops, is very difficult to treat. When a large ischemic area with signs of infection is present, as was the case in this ALI patient, we believe that early blood purification therapy after revascularization can contribute to the stabilization of the general state of the patient, and can help prevent a reperfusion injury, which may save the patient’s life. </p>

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