Medical Opioid Disposal in Fukuoka and Kumamoto Cities

  • Ota Asami
    Department of Clinical Pharmacy and Pharmaceutical Care, Graduate School of Pharmaceutical Sciences, Kyushu University Department of Health and Social Services, Kumamoto Prefecture Government
  • Kurata Shinnosuke
    Department of Clinical Pharmacy and Pharmaceutical Care, Graduate School of Pharmaceutical Sciences, Kyushu University
  • Tatsuma Kaho
    Department of Clinical Pharmacy and Pharmaceutical Care, Graduate School of Pharmaceutical Sciences, Kyushu University
  • Isaka Hinako
    Department of Clinical Pharmacy and Pharmaceutical Care, Graduate School of Pharmaceutical Sciences, Kyushu University
  • Higuchi Yoshinori
    Department of Health and Social Services, Kumamoto Prefecture Government
  • Nishina Takeshi
    Department of Health and Social Services, Kumamoto Prefecture Government
  • Haraguchi Keiko
    Fukuoka City Pharmaceutical Association
  • Takaki Junichi
    Fukuoka City Pharmaceutical Association
  • Kihara Taro
    Fukuoka City Pharmaceutical Association
  • Tanaka Taizo
    Fukuoka City Pharmaceutical Association
  • Amagata Tomoko
    Heartfelt Inc.
  • Inaba Ichiro
    Heartfelt Inc.
  • Kawashiri Takehiro
    Department of Clinical Pharmacy and Pharmaceutical Care, Graduate School of Pharmaceutical Sciences, Kyushu University
  • Kobayashi Daisuke
    Department of Clinical Pharmacy and Pharmaceutical Care, Graduate School of Pharmaceutical Sciences, Kyushu University
  • Shimazoe Takao
    Department of Clinical Pharmacy and Pharmaceutical Care, Graduate School of Pharmaceutical Sciences, Kyushu University

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Description

<p>Medical expenses are increasing year by year in Japan. However, the quantity of disposed medical opioids is not well known. In this study, we assessed disposed medical opioids in community pharmacies of Fukuoka city and in all of medical organizations of Kumamoto cities for 3 and 2 years, respectively. We collected official opioid disposal reports in Kumamoto city and Fukuoka City Pharmaceutical Association (FCPA) disposal information sheet in Fukuoka city. The total amount of disposed opioids was worth 7.1 million Yen from 2017 to 2019 in Fukuoka city, and 8.9 million Yen in for 2 years (2018 and 2019) in Kumamoto city. In Fukuoka city, the most disposed opioid was 20 mg Oxycontin®, worth approximately 940000 Yen. In Kumamoto city we assessed data in different organizations. The most disposed opioid was 5 mg Oxinorm® at a cost of 600000 Yen at the medical institutions over the 2-year study period. The most disposed opioid was 40 mg Oxycontin®, at a cost of 640000 Yen in community pharmacies. Two hundred micrograms E-fen® buccal tablet was the most disposed of opioid, was amounting to 960000 Yen in wholesalers. On the whole in Kumamoto city, non-dispensing was the most common reason of disposal. These results indicate that the amount of disposed opioids is huge. Small package simulation studies suggest that smaller package units of MS-Contin®, Anpec® suppository, and Abstral® sublingual tablet may be able to reduce the amount of disposed opioids.</p>

Journal

  • YAKUGAKU ZASSHI

    YAKUGAKU ZASSHI 143 (5), 459-464, 2023-05-01

    The Pharmaceutical Society of Japan

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