Association of Left Atrial Size With Stroke or Systemic Embolism in Patients With Atrial Fibrillation Having Undergone Bioprosthetic Valve Replacement From the BPV-AF Registry

DOI Web Site 参考文献18件
  • Tanaka Hidekazu
    Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine
  • Takegami Misa
    Department of Preventive Medicine and Epidemiology, National Cerebral and Cardiovascular Center
  • Miyake Makoto
    Department of Cardiology, Tenri Hospital
  • Amano Masashi
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
  • Kitai Takeshi
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital
  • Fujita Tomoyuki
    Cardiovascular Surgery Department, National Cerebral and Cardiovascular Center
  • Koyama Tadaaki
    Department of Cardiovascular Surgery, Kobe City Medical Center General Hospital
  • Ando Kenji
    Department of Cardiology, Kokura Memorial Hospital
  • Komiya Tatsuhiko
    Department of Cardiovascular Surgery, Kurashiki Central Hospital
  • Izumo Masaki
    Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine
  • Kawai Hiroya
    Department of Cardiology, Hyogo Prefectural Harima-Himeji General Medical Center
  • Eishi Kiyoyuki
    Department of Cardiovascular Surgery, Nagasaki University Hospital
  • Yoshida Kiyoshi
    Department of Cardiology, The Sakakibara Heart Institute of Okayama
  • Kimura Takeshi
    Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University
  • Nawada Ryuzo
    Department of Cardiology, Shizuoka City Shizuoka Hospital
  • Sakamoto Tomohiro
    Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center
  • Shibata Yoshisato
    Department of Cardiology, Miyazaki Medical Association Hospital Cardiovascular Center
  • Fukui Toshihiro
    Department of Cardiovascular Surgery, Graduate School of Medical Sciences, Kumamoto University
  • Minatoya Kenji
    Department of Cardiovascular Surgery, Graduate School of Medicine, Kyoto University
  • Tsujita Kenichi
    Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University
  • Sakata Yasushi
    Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine
  • Kimura Tetsuya
    Primary Medical Science Department, Daiichi Sankyo Co., Ltd.
  • Nishimura Kunihiro
    Department of Preventive Medicine and Epidemiology, National Cerebral and Cardiovascular Center
  • Furukawa Yutaka
    Department of Cardiovascular Medicine, Kobe City Medical Center General Hospital
  • Izumi Chisato
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
  • for the BPV-AF Registry Group

抄録

<p>Background: The left atrial volume index (LAVI) is important for predicting thromboembolism in patients with non-valvular atrial fibrillation (AF), but the utility of LAVI for predicting thromboembolism in patients with both bioprosthetic valve replacement and AF remains unclear.</p><p>Methods and Results: Of 894 patients from a previous multicenter prospective observational registry (BPV-AF Registry), 533 whose LAVI data had been obtained by transthoracic echocardiography were included in this subanalysis. Patients were divided into tertiles (T1–T3) according to LAVI as follows: T1 (n=177), LAVI=21.5–55.3 mL/m2; T2 (n=178), LAVI=55.6–82.1 mL/m2; T3 (n=178), LAVI=82.5–408.0 mL/m2. The primary outcome was defined as either stroke or systemic embolism for a mean (±SD) follow-up period of 15.3±4.2 months. Kaplan-Meier curves indicated that the primary outcome tended to occur more frequently in the group with the larger LAVI (log-rank P=0.098). Comparison of T1 with T2 plus T3 using Kaplan-Meier curves indicated that patients in T1 experienced significantly fewer primary outcomes (log-rank P=0.028). Furthermore, univariate Cox proportional hazard regression showed that 1.3- and 3.3-fold more primary outcomes occurred in T2 and T3, respectively, than in T1.</p><p>Conclusions: Larger LAVI was associated with stroke or systemic embolism in patients who had undergone bioprosthetic valve replacement and with a definitive diagnosis of AF.</p>

収録刊行物

  • Circulation Reports

    Circulation Reports 5 (5), 210-216, 2023-05-10

    一般社団法人 日本循環器学会

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